Thrift Library’s collection contains over 72,000 physical (print) volumes, more than 1.8 million ebooks, and approximately 200 electronic research, reference, and subject-specific databases that provide access to countless scholarly journals, periodicals, ebooks, digital images, and audio and video recordings. Thrift Library’s collections are greatly enhanced by resource sharing and collaborative licensing of digital resources through its membership in the state’s academic library consortium, PASCAL (Partnership among South Carolina Academic Libraries), reciprocal borrowing agreements with Atla and Association of Christian Librarians, and partnership with the Anderson County Library System.
The majority of the Thrift Library print collection is located on the second floor of the main library.
The book stacks are organized by Library of Congress (LC) classification:
| Label | Category |
| A | General Works |
| B | Philosophy, Psychology, & Religion |
| C | Auxillary Science of History |
| D | History: General/Old World |
| E-F | History: The Americas |
| G | Geography |
| H | Social Sciences |
| J | Political Science |
| K | Law |
| L | Education |
| M | Music |
| N | Fine Arts |
| P | Literature & Language |
| Q | Sciences |
| S | Agriculture |
| T | Technology |
| U | Military Science |
| V | Naval Science |
| Z | Bibliography & Library Science |